AMERICA'S #1 TRUSTED SLEEP AID
M.D. FORMULATED
72/100
SUPPIE SCORE
62/100
EFFICACY
Medium
SAFETY
92/100
CLEANLINESS
What Does M.D. FORMULATED Do?
Formula centers on 100 mg magnesium oxide, 500 mg L-tryptophan, a 125 mg valerian/hops/ashwagandha blend, 100 mg GABA/chamomile/passionflower, and undisclosed melatonin; evidence for sleep parameters is mixed and limited at these exact doses and forms.
What is the exact melatonin amount in this formula?
How does the Valerest blend compare to studied doses of valerian and hops?
Is the magnesium oxide form well absorbed for sleep support?
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What Are the Benefits of M.D. FORMULATED?
Based on proven scientific research
Sleep onsetModerate
Sleep qualityModerate
Relaxation supportMild
Anxiety reductionMild
Good For:
What Are the Side Effects of AMERICA'S #1 TRUSTED SLEEP AID M.D. FORMULATED?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•Magnesium oxide 100 mg elemental may cause loose stools at higher intakes.
•Melatonin dose undisclosed; typical studied ranges 0.5-5 mg carry next-day drowsiness risk.
•Ashwagandha 8% withanolides extract may interact with thyroid medications or sedatives.
•Valerian and passionflower extracts can potentiate CNS depressants or alcohol.
•Evidence limited on long-term safety of this specific multi-herb combination.
Potential Side Effects
Negative Interactions
Allergens
Chamomile may cross-react in ragweed or Asteraceae allergies
Inactive Ingredients
Hypromellose (veggie capsule)
Low RiskDicalcium phosphate
Low RiskSilica
Low RiskMagnesium stearate. valerest is a
Low RiskMagnesium stearate
Low RiskWhat Are the Ingredients in AMERICA'S #1 TRUSTED SLEEP AID M.D. FORMULATED?
Magnesium (as magnesium oxide
100 mg
Magnesium citrate and magnesium bisglycinate complex L-Tryptophan Valerest* Proprietar Blend of
500 mg
Valerian (Valeria..) officinalis) (root) extract 5:1, Hops (Humulus lupulus) (aerial part) extract 10:1 Ashwagandha (Withania somnifera)
125 mg
(root and leaf) extract (standardized to 8% withanolide glycoside conjugates) GABA (Gamma-aminobutyric Acid) Chamomile (Matricaria recutita)
100 mg
[flower] powder Passionflower (Passiflora incarnata) [flower] extract 10:1 Melatonin
75 mg
Hypromellose (Veggie Capsule)
Dicalcium Phosphate
Silica
Magnesium Stearate. Valerest is a
Magnesium Stearate
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Dosage & Bioavailability
How the active doses and forms in M.D. FORMULATED compare to the research.
•L-Tryptophan — 500 mg; meta-analyses indicate ≥1 g doses shorten wake after sleep onset more reliably, placing this amount below the stronger evidence threshold.
•Ashwagandha (root and leaf) extract (standardized to 8% withanolide glycoside conjugates) — 125 mg blend component.
Sources & References
PMC13075487
Information from pmc.ncbi.nlm.nih.gov
PMC7911806
Information from pmc.ncbi.nlm.nih.gov
33942088
Information from pubmed.ncbi.nlm.nih.gov
38309227
Information from pubmed.ncbi.nlm.nih.gov
PMC13094296
Information from pmc.ncbi.nlm.nih.gov
Magnesium HealthProfessional
Information from ods.od.nih.gov
Frequently Asked Questions
Common questions about AMERICA'S #1 TRUSTED SLEEP AID M.D. FORMULATED