Designs for Health
B-Supreme
69/100
SUPPIE SCORE
88/100
EFFICACY
Medium
SAFETY
64/100
CLEANLINESS
What Does B-Supreme Do?
This premium B-complex offers high bioavailability with active forms and supportive CoQ10 for excellent energy, stress, and nervous system benefits. Dosages are mostly optimal but B6 at 50 mg warrants monitoring for long-term neuropathy risk; overall safe for short-term use.
What are the benefits of using active forms like pyridoxal-5-phosphate and mecobalamin in this B-complex?
How does the inclusion of CoQ10 and choline enhance the formula's support for energy production?
Is this supplement suitable for vegetarians or those with methylation issues?
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What Are the Benefits of B-Supreme?
Based on proven scientific research
Energy ProductionVery strong
Nervous System HealthVery strong
Stress ResponseStrong
Neurotransmitter SynthesisStrong
Glucose MetabolismModerate
Good For:
What Are the Side Effects of Designs for Health B-Supreme?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•The 50 mg dose of vitamin B6 (as pyridoxal-5-phosphate) exceeds the Australian upper limit of 50 mg and may pose a risk of peripheral neuropathy with long-term use, though the active form may reduce this risk compared to pyridoxine HCl.
•High doses of thiamine (100 mg) and riboflavin (50 mg) are well within safe limits with no known adverse effects at these levels for healthy adults.
•Folate as Quatrefolic (500 mcg levomefolic acid) is safe and preferred for those with MTHFR mutations; avoid in undiagnosed pernicious anemia without B12 confirmation.
•Mecobalamin (250 mcg), biotin (2 mg), pantothenic acid (100 mg), and niacinamide (50 mg) are at dosages well below safe upper limits, with minimal interaction risks.
•Ubidecarenone (CoQ10, 50 mg) and choline (82 mg) are safe at these levels; however, do not use concurrently with warfarin without medical advice due to potential anticoagulant interactions.
•Product contains no gluten, dairy, soy, or nuts; suitable for vegetarians, but consult healthcare provider if pregnant, breastfeeding, or on medications.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
What Are the Ingredients in Designs for Health B-Supreme?
Pyridoxal-5-phosphate monohydrate
78.37 mg (equiv. Pyridoxine 50 mg)
Mecobalamin
250 micrograms
Calcium pantothenate
109.17 mg (equiv. Pantothenic acid 100 mg)
Thiamine hydrochloride
112.15 mg (equiv. Thiamine 100 mg)
Riboflavin sodium phosphate
68.49 mg (equiv. Riboflavin 50 mg)
Levomefolate Glucosamine
901.7 micrograms (equiv. Levomefolic acid 500 micrograms)
Nicotinamide
50 mg
Biotin
2 mg
Ubidecarenone
50 mg
Choline bitartrate
200 mg (equiv. Choline 82.26 mg)
Colloidal anhydrous silica
Hypromellose
Magnesium stearate
Purified water
Silicon dioxide
Chlorophyllin – copper complex
Sources & References
Products
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Patient education b supreme
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B supreme
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Niacinamide
Information from www.webmd.com
Products
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B00290I4NO
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22273.pdf
Information from api.ods.od.nih.gov
B supreme by designs health 1771062542
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Designs for health b supreme 60 vegetarian capsules
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B supreme 60 vegcaps
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Designs for health b supreme 120 vegetarian capsules
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P
Information from www.anuaesthetics.com
Vitamin b3 nicotinamide glaucoma
Information from www.aao.org
Bsupreme by designs for health
Information from www.pureformulas.com
Peripheral neuropathy supplementary vitamin b6 pyridoxine
Information from www.tga.gov.au
NBK554500
Information from www.ncbi.nlm.nih.gov
Designs for health b supreme 120 vegetarian capsules
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Liposomal b supreme
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390939
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Products
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B002MAT56G
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High dose vitamin b6 and risk of peripheral neuropathy
Information from www.hsa.gov.sg
Niacinamide
Information from www.komen.org
Art 20363468
Information from www.mayoclinic.org
Products
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Vitamin b6 safe electrolyte drinks supplements what to know rcna252639
Information from www.nbcnews.com
B supreme 120 vcaps
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Information from supplementfirst.com
Products
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0520574c249f42af8a76c918d9c7a3be
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Products
Information from www.nhc.com
Designs for health designs for health b supreme 60vc
Information from www.australianvitamins.com
Bsupreme by designs for health
Information from www.pureformulas.com
B supreme caps
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Designs for health b supreme 60 vegetarian capsules
Information from www.iherb.com
Frequently Asked Questions
Common questions about Designs for Health B-Supreme