Double Wood
BERBERINE
78/100
SUPPIE SCORE
78/100
EFFICACY
Medium
SAFETY
94/100
CLEANLINESS
What Does BERBERINE Do?
Double Wood Berberine delivers a straightforward 500 mg HCl dose that aligns with amounts used in multiple meta-analyses for metabolic and cardiovascular markers, though its inherently low bioavailability means split dosing is typical in research.
How does berberine compare to metformin for blood sugar support?
What is the best way to take berberine to minimize digestive upset?
Can berberine be combined with other metabolic supplements?
Chat with Suppie
What Are the Benefits of BERBERINE?
Based on proven scientific research
Blood Sugar ControlStrong
Cholesterol BalanceModerate
Metabolic HealthStrong
Cardiovascular SupportModerate
AMPK ActivationModerate
Good For:
What Are the Side Effects of Double Wood BERBERINE?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•Berberine HCl at 500 mg is generally well-tolerated but GI side effects like nausea, diarrhea, or constipation are common, especially at higher daily intakes.
•Known to inhibit CYP3A4 and P-gp, leading to major interactions with drugs like cyclosporine, metformin, and certain statins.
•Low systemic bioavailability (<1%) due to poor absorption and rapid metabolism; may require divided dosing with meals.
•Avoid during pregnancy or breastfeeding due to potential uterine stimulant effects and limited safety data.
•May lower blood glucose or blood pressure excessively when combined with antidiabetic or antihypertensive medications.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Hypromellose
Low RiskMicrocrystalline cellulose
Low RiskSilicon dioxide
Low RiskWhat Are the Ingredients in Double Wood BERBERINE?
Berberine HCl
500 mg
Hypromellose
Microcrystalline Cellulose
Silicon Dioxide
Scan the bottle in your cupboard
Same graded report you just read — on any label, in about 10 seconds.
Dosage & Bioavailability
How the active doses and forms in BERBERINE compare to the research.
•Berberine HCl is listed at 500 mg per serving; without a source-specific reference range, dose adequacy cannot be graded.
•Berberine HCl has no distinct chemical or delivery form stated, so no product-specific absorption advantage can be established.
Frequently Asked Questions
Common questions about Double Wood BERBERINE