DrinkDefendly
DrinkDefendly Alcohol Defence
80/100
SUPPIE SCORE
58/100
EFFICACY
High
SAFETY
90/100
CLEANLINESS
What Does DrinkDefendly Alcohol Defence Do?
DrinkDefendly provides dihydromyricetin, botanical extracts, and vitamins to mitigate next-day alcohol discomfort, though clinical evidence in humans remains preliminary.
When is the best time to take DrinkDefendly relative to alcohol consumption?
Does 1200 mg of dihydromyricetin completely prevent alcohol intoxication or hangovers?
Can DrinkDefendly interact with my prescription medications or liver enzymes?
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What Are the Benefits of DrinkDefendly Alcohol Defence?
Based on proven scientific research
Alcohol Hangover DiscomfortMild
Post-Alcohol Nausea ReliefMild
Antioxidant SupportModerate
B-Vitamin ReplenishmentStrong
Good For:
What Are the Side Effects of DrinkDefendly DrinkDefendly Alcohol Defence?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Vitamin B6: 20 mg a day is above the 12 mg/day EU upper limit (EFSA 2023), though within the US limit of 100 mg/day. Taking more than this for months is linked to nerve damage (peripheral neuropathy: numbness, tingling or pain in hands and feet), which usually improves after stopping.
•Dihydromyricetin, ginger, and milk thistle are generally well tolerated, with mild gastrointestinal discomfort being the primary reported side effect.
•Contains 20 mg of vitamin B6 (as pyridoxine HCl) per 3 capsules, which exceeds the EFSA daily guidance limit of 12 mg; avoid combining with other high-dose B6 supplements.
•Vitamin E is provided at 90 mg (90 IU), which is well below established upper intake limits but may exert mild antiplatelet effects when combined with anticoagulants.
•Not evaluated or recommended for use during pregnancy, lactation, or by individuals with significant hepatic or renal impairment.
•This product does not accelerate alcohol clearance, reduce blood alcohol concentration, or prevent alcohol-induced cognitive and motor impairment.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Vegetarian capsule
Low RiskSilicon dioxide
Low RiskMagnesium stearate
Low RiskMicrocrystalline cellulose
Low RiskWhat Are the Ingredients in DrinkDefendly DrinkDefendly Alcohol Defence?
Vitamin C (as ascorbic acid)
75 mg
Vitamin E (as d-alpha tocopheryl acetate)
90 mg
Thiamin (Vitamin B1) (as thiamin HCl)
20 mg
Vitamin B6 (as pyridoxine HCl)
20 mg
Vitamin B12 (as cyanocobalamin)
100 mcg
Sodium (as sodium chloride)
15 mg
Potassium (as potassium citrate)
15 mg
Vine Tea (Ampelopsis grossedentata) (Aerial) Extract (std. to 98% Dihydromyricetin)
1200 mg
Milk Thistle (Silybum marianum) (seed) Extract (std to 80% Silymarin)
50 mg
Prickly Pear (Opuntia ficus-indica) (fruit)
50 mg
Ginger (Zingiber officinale) (root) Extract (std. to 5% Gingerols)
50 mg
Vegetarian Capsule
Silicon Dioxide
Magnesium Stearate
Microcrystalline Cellulose
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Dosage & Bioavailability
How the active doses and forms in DrinkDefendly Alcohol Defence compare to the research.
•Formula — 11 actives: 1 over its upper limit (vitamin B6), 5 below studied amounts, 4 of them by more than half (vitamin E, sodium and 3 more), 2 within studied amounts and 2 meeting daily needs.
•Vitamin B6 (as pyridoxine HCl) — 20 mg a day is over the 12 mg/day upper limit (EFSA 2023); the US limit is 100 mg/day (IOM (NIH ODS)).
•Vitamins and minerals — 4 of 5 provide at least 90% of the daily reference intake: vitamin B12 (about 40 times), thiamin (about 16 times), plus 2 more; potassium supplies less.
Frequently Asked Questions
Common questions about DrinkDefendly DrinkDefendly Alcohol Defence