Herbal Factors
Millepertuis
76/100
SUPPIE SCORE
72/100
EFFICACY
Medium
SAFETY
94/100
CLEANLINESS
What Does Millepertuis Do?
Herbal Factors Millepertuis provides a standardized 300 mg St. John's Wort extract at the commonly studied 0.3% hypericin level, with meta-analyses supporting moderate benefits for mild-to-moderate depression, nervousness, and related sleep issues comparable.
What symptoms are you hoping this supplement will help relieve?
Are you currently taking any prescription medications or have any health conditions?
How long have you been experiencing nervousness or sleep issues?
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What Are the Benefits of Millepertuis?
Based on proven scientific research
Mood balanceModerate
Nervousness reliefStrong
Sleep supportModerate
Mild depression symptomsModerate
Good For:
What Are the Side Effects of Herbal Factors Millepertuis?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•Standardized St. John's Wort at 900 mg daily (0.3% hypericin) is generally well-tolerated in short-term use up to 6-12 weeks.
•Common side effects include photosensitivity, dry mouth, dizziness, and gastrointestinal upset; avoid prolonged sun/UV exposure.
•Significant herb-drug interactions via CYP3A4 and P-gp induction; contraindicated with antidepressants (SSRIs, MAOIs), contraceptives, digoxin, warfarin, antiretrovirals, and anticonvulsants.
•Not for use in pregnancy, breastfeeding, bipolar disorder (risk of mania), or with known allergies to the plant.
•Label limits use to maximum 6 weeks without practitioner supervision; consult healthcare provider if symptoms persist or before combining with medications.
•Product free of major allergens (dairy, gluten, soy, nuts, etc.) and artificial additives.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Poudre de riz
Low RiskCapsule de gélatine (gélatine, eau purifiée)
Low RiskStéarate de magnésium d'origine végétale
Low RiskSilice
Low RiskWhat Are the Ingredients in Herbal Factors Millepertuis?
Millepertuis (Hypericum perforatum) (parties aériennes)
300 mg
poudre de riz
capsule de gélatine (gélatine, eau purifiée)
stéarate de magnésium d'origine végétale
silice
Dosage & Bioavailability
How the active doses and forms in Millepertuis compare to the research.
•Millepertuis (Hypericum perforatum) — 300 mg per capsule (900 mg daily); within 300-1800 mg/day range studied in multiple RCTs and meta-analyses for mild-moderate depression.
•Millepertuis (Hypericum perforatum) — standardized to 0.3% hypericin (0.9 mg per capsule); hypericin and hyperforin show low oral bioavailability of 14-21% with variable.
Sources & References
Millepertuis herbalfactors
Information from ca.naturalfactors.com
10439477
Information from pubmed.ncbi.nlm.nih.gov
8878586
Information from pubmed.ncbi.nlm.nih.gov
PMC9526892
Information from pmc.ncbi.nlm.nih.gov
PMC12622987
Information from pmc.ncbi.nlm.nih.gov
PMC28296
Information from pmc.ncbi.nlm.nih.gov
Frequently Asked Questions
Common questions about Herbal Factors Millepertuis