INTEGRATIVE THERAPEUTICS
ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE
91/100
SUPPIE SCORE
88/100
EFFICACY
High
SAFETY
94/100
CLEANLINESS
What Does ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE Do?
High-bioavailability active B-vitamins at clinically relevant doses with low-risk excipients; monitor B6 intake long-term.
How does the methylated folate and B12 combination compare to standard folic acid supplements?
What makes the active B-vitamin forms in this formula more bioavailable than conventional B-complexes?
Is the 1,000 mcg methylcobalamin dose safe for daily long-term use?
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What Are the Benefits of ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE?
Based on proven scientific research
Energy metabolismVery strong
Nervous system supportStrong
Mood regulationStrong
Cardiovascular healthModerate
Homocysteine reductionStrong
Good For:
What Are the Side Effects of INTEGRATIVE THERAPEUTICS ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•High-dose B6 (50 mg) may cause reversible peripheral neuropathy with prolonged daily use exceeding 100 mg.
•Methylfolate and methylcobalamin are generally well-tolerated but can cause transient irritability or insomnia in sensitive individuals.
•Safe for most adults at recommended dose; consult physician if pregnant, nursing, or taking anticonvulsants.
•Contains no common allergens but individuals with corn sensitivity should verify capsule sourcing.
•Choline bitartrate at 120 mg is well below the 3.5 g daily upper limit and unlikely to cause fishy body odor.
•No significant drug interactions expected at these doses, but high-dose niacin may potentiate statin-related myopathy.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Plant-derived capsule (hypromellose)
Low RiskCellulose
Low RiskMagnesium stearate
Low RiskAscorbyl palmitate
GoodSilica
Low RiskWhat Are the Ingredients in INTEGRATIVE THERAPEUTICS ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE?
Thiamin (Vitamin B1)
50 mg
Riboflavin (Vitamin B2)
50 mg
Niacin (Vitamin B3)
100 mg
Vitamin B6 (as pyridoxal-5-phosphate)
50 mg
Folate (Quatrefolic® brand (6S)-5-methyltetrahydrofolate glucosamine salt)
1,837 mcg DFE
Vitamin B12 (as methylcobalamin)
1,000 mcg
Pantothenic Acid (Vitamin B5)
100 mg
Choline (as choline bitartrate)
120 mg
plant-derived capsule (hypromellose)
cellulose
magnesium stearate
ascorbyl palmitate
silica
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Dosage & Bioavailability
How the active doses and forms in ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE compare to the research.
•Thiamin (Vitamin B1) is listed at 50 mg per serving; without a source-specific reference range, dose adequacy cannot be graded.
•Riboflavin (Vitamin B2) is listed at 50 mg per serving; without a source-specific reference range, dose adequacy cannot be graded.
Sources & References
No sources available
Frequently Asked Questions
Common questions about INTEGRATIVE THERAPEUTICS ACTIVE B-COMPLEX WITH QUATREFOLIC® BRAND METHYLFOLATE