Life Extension
Benfotiamine with Thiamine
85/100
SUPPIE SCORE
68/100
EFFICACY
High
SAFETY
94/100
CLEANLINESS
What Does Benfotiamine with Thiamine Do?
Benfotiamine 100 mg plus thiamine HCl 25 mg supplies a fat-soluble thiamine source with ~5-fold higher bioavailability than standard thiamine; trials at 300 mg+ show signals for neuropathy pain and modest cognitive preservation.
How does 100 mg benfotiamine compare to standard thiamine doses for neuropathy?
What evidence supports benfotiamine for cognitive outcomes at this dose?
Are there any known interactions between benfotiamine and common medications?
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What Are the Benefits of Benfotiamine with Thiamine?
Based on proven scientific research
Neuropathy pain reductionModerate
Diabetic complication supportModerate
Thiamine repletionStrong
Cognitive decline slowingMild
Good For:
What Are the Side Effects of Life Extension Benfotiamine with Thiamine?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Benfotiamine doses up to 1200 mg single and 600 mg multiple daily showed mild or moderate AEs similar to placebo in healthy subjects.
•Common drug-related AEs in trials included increased ALT and urinary WBC, occurring at low rates.
•Thiamine has no established upper limit; evidence limited on high-dose use in pregnancy.
•Benfotiamine reduced AGEs in one AD trial with no major safety signals reported.
Potential Side Effects
Negative Interactions
Allergens
No allergen declarations tied to the active ingredients in verified facts
Inactive Ingredients
Microcrystalline cellulose
Low RiskVegetable cellulose (capsule)
Low RiskSilica
Low RiskVegetable stearate
Low RiskWhat Are the Ingredients in Life Extension Benfotiamine with Thiamine?
Thiamine (vitamin B1) (as thiamine HCl)
25 mg
Benfotiamine
100 mg
microcrystalline cellulose
vegetable cellulose (capsule)
silica
vegetable stearate
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Dosage & Bioavailability
How the active doses and forms in Benfotiamine with Thiamine compare to the research.
•Benfotiamine — 100 mg; absorption approximately 5-fold higher than thiamine and 3.7-fold higher than thiamine hydrochloride per examined pharmacokinetic data.
•Benfotiamine — 100 mg; the label does not disclose an extract standardisation percentage or marker amount.
Sources & References
Frequently Asked Questions
Common questions about Life Extension Benfotiamine with Thiamine