Life Extension
BioActive Folate & Vitamin B12
87/100
SUPPIE SCORE
82/100
EFFICACY
High
SAFETY
88/100
CLEANLINESS
What Does BioActive Folate & Vitamin B12 Do?
- Folate is provided as bioactive L-5-MTHF at 680 mcg DFE, within common daily target ranges.
- Vitamin B12 is a clearly disclosed 300 mcg methylcobalamin dose, a bioactive form.
- No proprietary blend is used, so active dosages are fully transparent.
Is this a good choice if I follow a vegan or vegetarian diet?
Can I take this with my multivitamin or B-complex?
How long might it take to notice benefits from folate and B12 support?
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What Are the Benefits of BioActive Folate & Vitamin B12?
Based on proven scientific research
Folate and B12 RepletionVery strong
Homocysteine SupportStrong
Red Blood Cell ProductionStrong
Nerve HealthModerate
Cognitive SupportModerate
Good For:
What Are the Side Effects of Life Extension BioActive Folate & Vitamin B12?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Provides 680 mcg DFE folate as L-5-MTHF and 300 mcg vitamin B12 as methylcobalamin; these are generally safe daily amounts for adults and are below the folic acid tolerable upper limit.
•Mild side effects are uncommon but may include nausea, bloating, headache, or skin reactions, especially in sensitive users starting high-dose B vitamins.
•Folate can interact with antifolate medicines such as methotrexate and may affect anticonvulsant therapy; people using these medications should ask a clinician before use.
•Metformin, proton-pump inhibitors, H2 blockers, and other acid-reducing medicines can reduce B12 status, so this product may be relevant but lab monitoring may still be needed.
•For pregnancy or trying to conceive, the folate amount aligns with common folate intake targets, but prenatal supplementation should be coordinated with a healthcare professional.
•The label lists gluten-free and vegetarian status with no major allergen ingredients declared; capsule and fillers are cellulose and dicalcium phosphate based.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Low Risk
Low Risk
Low Risk
What Are the Ingredients in Life Extension BioActive Folate & Vitamin B12?
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg DFE
Vitamin B12 (as methylcobalamin)
300 mcg
microcrystalline cellulose
vegetable cellulose (capsule)
dicalcium phosphate
Sources & References
Bioactive folate vitamin b12
Information from www.lifeextension.com
BioActive Folate Vitamin B12 90 vegetarian capsules
Information from lifeextensionvitamins.com
Bioactive folate vitamin b12
Information from www.lifeextensioneurope.com
Bioactive folate vitamin b12
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Bioactive folate vitamin b12.html
Information from www.lifeextension.asia
Bioactive folate vitamin b12
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Item01945
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Frequently Asked Questions
Common questions about Life Extension BioActive Folate & Vitamin B12