Life Extension
BioActive Folate & Vitamin B12
90/100
SUPPIE SCORE
82/100
EFFICACY
High
SAFETY
96/100
CLEANLINESS
What Does BioActive Folate & Vitamin B12 Do?
BioActive Folate & Vitamin B12 lists Folate (as L-5-methyltetrahydrofolate calcium salt) (680 mcg DFE) and Vitamin B12 (as methylcobalamin) (300 mcg) as its main actives. Any judgement should be based on the stated amounts and forms rather than the product name or marketing claims alone.
Is this a good choice if I follow a vegan or vegetarian diet?
Can I take this with my multivitamin or B-complex?
How long might it take to notice benefits from folate and B12 support?
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What Are the Benefits of BioActive Folate & Vitamin B12?
Based on proven scientific research
Folate and B12 RepletionVery strong
Homocysteine SupportStrong
Red Blood Cell ProductionStrong
Nerve HealthModerate
Cognitive SupportModerate
Good For:
What Are the Side Effects of Life Extension BioActive Folate & Vitamin B12?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Provides 680 mcg DFE folate as L-5-MTHF and 300 mcg vitamin B12 as methylcobalamin; these are generally safe daily amounts for adults and are below the folic acid tolerable upper limit.
•Mild side effects are uncommon but may include nausea, bloating, headache, or skin reactions, especially in sensitive users starting high-dose B vitamins.
•Folate can interact with antifolate medicines such as methotrexate and may affect anticonvulsant therapy; people using these medications should ask a clinician before use.
•Metformin, proton-pump inhibitors, H2 blockers, and other acid-reducing medicines can reduce B12 status, so this product may be relevant but lab monitoring may still be needed.
•For pregnancy or trying to conceive, the folate amount aligns with common folate intake targets, but prenatal supplementation should be coordinated with a healthcare professional.
•The label lists gluten-free and vegetarian status with no major allergen ingredients declared; capsule and fillers are cellulose and dicalcium phosphate based.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Microcrystalline cellulose
Low RiskVegetable cellulose (capsule)
Low RiskDicalcium phosphate
Low RiskWhat Are the Ingredients in Life Extension BioActive Folate & Vitamin B12?
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg DFE
Vitamin B12 (as methylcobalamin)
300 mcg
microcrystalline cellulose
vegetable cellulose (capsule)
dicalcium phosphate
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Dosage & Bioavailability
How the active doses and forms in BioActive Folate & Vitamin B12 compare to the research.
•Folate (as L-5-methyltetrahydrofolate calcium salt) is listed at 680 mcg DFE per serving; without a source-specific reference range, dose adequacy cannot be graded.
•Vitamin B12 (as methylcobalamin) is listed at 300 mcg per serving; without a source-specific reference range, dose adequacy cannot be graded.
Sources & References
Bioactive folate vitamin b12
Information from www.lifeextension.com
BioActive Folate Vitamin B12 90 vegetarian capsules
Information from lifeextensionvitamins.com
Bioactive folate vitamin b12
Information from www.lifeextensioneurope.com
Bioactive folate vitamin b12
Information from www.lifeextensioneurope.nl
Bioactive folate vitamin b12.html
Information from www.lifeextension.asia
Bioactive folate vitamin b12
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Frequently Asked Questions
Common questions about Life Extension BioActive Folate & Vitamin B12