Life Extension
Lithium
87/100
SUPPIE SCORE
75/100
EFFICACY
High
SAFETY
94/100
CLEANLINESS
What Does Lithium Do?
Life Extension Lithium offers a safe, low-dose 1000 mcg lithium orotate formulation supporting brain health and cognitive function with emerging evidence from animal studies and limited human trials. Inactive ingredients pose no concerns; overall value is high for preventive use, though human data remains preliminary.
What are the potential cognitive benefits of lithium orotate supplementation?
How does the dosage of 1000 mcg compare to therapeutic levels of lithium?
Are there any long-term effects of low-dose lithium on brain health?
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What Are the Benefits of Lithium?
Based on proven scientific research
Cognitive FunctionModerate
Mood SupportMild
NeuroprotectionModerate
Memory EnhancementMild
Good For:
What Are the Side Effects of Life Extension Lithium?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•At 1000 mcg, lithium orotate is well within safe low-dose ranges (300-1000 mcg), minimizing risks associated with higher therapeutic doses like renal impairment or hypothyroidism.
•Potential mild side effects include nausea, diarrhea, or dizziness in sensitive individuals; severe effects are rare at this dosage.
•May interact with diuretics, NSAIDs, or ACE inhibitors by altering lithium excretion, potentially increasing toxicity risk—monitor if on such medications.
•Contraindicated in pregnancy due to risk of congenital malformations, particularly cardiac issues in the first trimester; avoid breastfeeding as lithium passes into milk.
•Safe for most healthy adults, but consult a doctor if you have kidney, thyroid, or heart conditions; no major allergens present.
•Long-term use appears safe based on emerging evidence, but periodic monitoring of kidney and thyroid function is advisable.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Low Risk
Low Risk
What Are the Ingredients in Life Extension Lithium?
Lithium (as lithium orotate)
1000 mcg
microcrystalline cellulose
vegetable cellulose (capsule)
Sources & References
Microcrystalline cellulose 48.html
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Lithium
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PMC11954165
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Lithium
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A proof of concept study of an accessible lithium supplement
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Lithium and its potential protection
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Gut check
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Comparing lithium orotate and prescription lithium for bipolar disorder
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Lithium orotate.html
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Lithium in pregnancy and breastfeeding
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Lithium.htm
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PMC8413749
Information from pmc.ncbi.nlm.nih.gov
What are the potential negative effects of lithium orotate
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NBK582797
Information from www.ncbi.nlm.nih.gov
Lithium and alzheimers
Information from peterattiamd.com
Low dose lithium a new frontier in mental health treatment
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Lithium orotate
Information from www.naturalmentalhealth.com
S41586 025 09335 x
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Supplements
Information from www.lifeextension.com
S0165032724008723
Information from www.sciencedirect.com
Lithium
Information from www.healthdirect.gov.au
Pregnancy breastfeeding and fertility while taking lithium
Information from www.nhs.uk
Are your supplements safe to consume watch out for these common fillers
Information from www.nongmoproject.org
Product
Information from hollyhillvitamins.com
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Information from www.lifeextension.com
Lithium orotate revisited
Information from www.science.org
Life extension lithium 1 000 mcg 100 vegetarian capsules
Information from www.iherb.com
Could lithium explain treat alzheimers disease
Information from hms.harvard.edu
Drg 20064603
Information from www.mayoclinic.org
Item02403
Information from www.lifeextension.com
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Information from www.lifeextension.com
PMC6274637
Information from pmc.ncbi.nlm.nih.gov
Life extension lithium 1 000 mcg 100 vegetarian capsules
Information from www.iherb.com
Frequently Asked Questions
Common questions about Life Extension Lithium