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Life Extension - SAMe 400 mg

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Life Extension

SAMe 400 mg

D grade
48/100
SUPPIE SCORE
82/100
EFFICACY
Medium
SAFETY
34/100
CLEANLINESS

What Does SAMe 400 mg Do?

• 400 mg SAMe dose aligns with many mood and joint studies. • Enteric coating protects SAMe from stomach acid degradation. • Recommendation to pair with B6, B12, and folate supports methylation pathways.
How does the 400 mg SAMe dosage compare to clinical studies for mood support?
Why is it recommended to take SAMe with B vitamins like B6, B12, and folic acid?
What makes the enteric coating important for SAMe absorption?
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What Are the Benefits of SAMe 400 mg?

Based on proven scientific research

Mood SupportStrong
Joint HealthStrong
Liver SupportModerate

Good For:

What Are the Side Effects of Life Extension SAMe 400 mg?

Always consult your health practitioner if in doubt.

RiskMedium Risk

Overview

Avoid if diagnosed with bipolar disorder due to mania risk
May interact with antidepressants and serotonergic drugs
Take on empty stomach for optimal absorption
Generally well-tolerated at recommended doses
Consult physician if pregnant or lactating
No major allergen concerns identified

Potential Side Effects

Negative Interactions

Inactive Ingredients

Cellulose
Low Risk
Methacrylic acid copolymer
Low Risk
Mannitol
Low Risk
Citric acid
Low Risk
Stearic acid
Low Risk
Silica
Low Risk
Hypromellose
Low Risk
Glyceryl triacetate
Low Risk
Sodium starch glycolate
Good
Croscarmellose sodium
Low Risk
Calcium carbonate
Low Risk
Yellow ochre
Low Risk

What Are the Ingredients in Life Extension SAMe 400 mg?

S-Adenosyl-Methionine
400 mg
cellulose
methacrylic acid copolymer
mannitol
citric acid
stearic acid
silica
hypromellose
glyceryl triacetate
sodium starch glycolate
croscarmellose sodium
calcium carbonate
yellow ochre

Frequently Asked Questions

Common questions about Life Extension SAMe 400 mg