Life Extension - TMG 500 mg, 60 liquid vegetarian capsules

Suppie Report

Life Extension

TMG 500 mg, 60 liquid vegetarian capsules

B grade
86/100
SUPPIE SCORE
78/100
EFFICACY
High
SAFETY
88/100
CLEANLINESS

What Does TMG 500 mg, 60 liquid vegetarian capsules Do?

This Life Extension TMG provides a full 1000 mg betaine anhydrous per serving, a dose aligned with studies supporting homocysteine reduction and cardiovascular benefits when paired with B-vitamin cofactors. Evidence is solid for methylation and liver support but more limited for broader claims like mitochondrial function at this exact amount.
How does TMG support healthy homocysteine levels when taken with B vitamins?
What is the best way to take this 1000 mg TMG dose for optimal absorption?
Can TMG at this dosage help with liver function or metabolic health?
Chat with Suppie

What Are the Benefits of TMG 500 mg, 60 liquid vegetarian capsules?

Based on proven scientific research

Healthy Homocysteine LevelsStrong
Cardiovascular HealthModerate
Liver Function SupportModerate
Mitochondrial and Cellular HealthMild

Good For:

What Are the Side Effects of Life Extension TMG 500 mg, 60 liquid vegetarian capsules?

Always consult your health practitioner if in doubt.

RiskLow Risk

Overview

At 1000 mg daily, TMG as betaine anhydrous is generally well-tolerated with low risk of side effects in healthy adults.
Best taken with B6, B12, and folic acid to support methylation pathways effectively.
No major concerns at this dose, but long-term high doses may require monitoring of lipid profiles in some individuals.
This vegetarian liquid capsule formulation has no common allergens like gluten or major food sensitivities.

Potential Side Effects

Negative Interactions

Allergens

None in this formulation

Inactive Ingredients

Glycerin
Low Risk
Vegetable cellulose (capsule)
Low Risk
Purified water. dosage
Low Risk
Use take two (2) capsules in the morning
Low Risk
Or as recommended by a healthcare practitioner. tmg should be taken with co-factors b6
Low Risk
B12
Low Risk
And folic acid
Low Risk
Cellulose
Low Risk

What Are the Ingredients in Life Extension TMG 500 mg, 60 liquid vegetarian capsules?

Trimethylglycine (TMG) (as betaine anhydrous)
1000 mg
glycerin
vegetable cellulose (capsule)
purified water. Dosage
Use Take two (2) capsules in the morning
or as recommended by a healthcare practitioner. TMG should be taken with co-factors B6
B12
and folic acid
Cellulose

Dosage & Bioavailability

How the active doses and forms in TMG 500 mg, 60 liquid vegetarian capsules compare to the research.

1000 mg (two capsules) matches doses used in homocysteine and metabolic trials for good efficacy.
Betaine anhydrous form offers high bioavailability as a direct methyl donor without needing conversion.
Morning dosing with B6/B12/folate optimizes absorption and methylation synergy; no hidden blends.

Frequently Asked Questions

Common questions about Life Extension TMG 500 mg, 60 liquid vegetarian capsules