Methyl
Methyl Folate
89/100
SUPPIE SCORE
85/100
EFFICACY
High
SAFETY
90/100
CLEANLINESS
What Does Methyl Folate Do?
Its main active, Folate, provides 1,700 mcg per serving, over the 1,000 mcg/day upper limit.
What is the difference between this methylfolate and regular folic acid?
How should I take this supplement for best absorption?
Can this be combined with a B12 or B-complex supplement?
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What Are the Benefits of Methyl Folate?
Based on proven scientific research
Neurological HealthModerate
Cell DivisionModerate
DNA SynthesisMild
Methylation SupportStrong
Good For:
What Are the Side Effects of Methyl Methyl Folate?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Provides 1000 mcg (6S)-5-MTHF as Quatrefolic glucosamine salt, a bioactive form that bypasses MTHFR conversion.
•High-dose folate may mask vitamin B12 deficiency; elderly or those with B12 absorption issues should monitor levels.
•Generally well-tolerated at this dose with low interaction potential beyond noted medications.
•Free of major allergens including wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Microcrystalline cellulose
Low RiskStearic acid (vegetable source)
Low RiskSilicon dioxide
Low RiskWhat Are the Ingredients in Methyl Methyl Folate?
Folate
1700 mcg DFE
(6S)-5-MTHF
1000 mcg
Microcrystalline Cellulose
Stearic Acid (vegetable source)
Silicon Dioxide
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Dosage & Bioavailability
How the active doses and forms in Methyl Folate compare to the research.
•Folate — 1,700 mcg per serving is over the 1,000 mcg/day upper limit (IOM (NIH ODS)).
•(6S)-5-MTHF — 1,000 mcg per serving; within the 400-1,360 mcg/day typically used in studies. It is at the 1,000 mcg/day upper limit for folic acid (IOM (NIH ODS)). This range is provisional until reviewed.
•(6S)-5-MTHF — 6s 5 mthf is one of the better-absorbed, well-studied forms of folate.
Sources & References
Frequently Asked Questions
Common questions about Methyl Methyl Folate