Methyl
Methyl Folate
90/100
SUPPIE SCORE
85/100
EFFICACY
High
SAFETY
94/100
CLEANLINESS
What Does Methyl Folate Do?
The label lists Folate (1700 mcg DFE) and (6S)-5-MTHF (1000 mcg) as its main actives. Any judgement should be based on the stated amounts and forms rather than the product name or marketing claims alone.
What is the difference between this methylfolate and regular folic acid?
How should I take this supplement for best absorption?
Can this be combined with a B12 or B-complex supplement?
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What Are the Benefits of Methyl Folate?
Based on proven scientific research
Neurological HealthModerate
Cell DivisionModerate
DNA SynthesisMild
Methylation SupportStrong
Good For:
What Are the Side Effects of Methyl Methyl Folate?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Provides 1000 mcg (6S)-5-MTHF as Quatrefolic glucosamine salt, a bioactive form that bypasses MTHFR conversion.
•High-dose folate may mask vitamin B12 deficiency; elderly or those with B12 absorption issues should monitor levels.
•Generally well-tolerated at this dose with low interaction potential beyond noted medications.
•Free of major allergens including wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Microcrystalline cellulose
Low RiskStearic acid (vegetable source)
Low RiskSilicon dioxide
Low RiskWhat Are the Ingredients in Methyl Methyl Folate?
Folate
1700 mcg DFE
(6S)-5-MTHF
1000 mcg
Microcrystalline Cellulose
Stearic Acid (vegetable source)
Silicon Dioxide
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Dosage & Bioavailability
How the active doses and forms in Methyl Folate compare to the research.
•Folate is listed at 1700 mcg DFE per serving; without a source-specific reference range, dose adequacy cannot be graded.
•(6S)-5-MTHF is listed at 1000 mcg per serving; without a source-specific reference range, dose adequacy cannot be graded.
Sources & References
Frequently Asked Questions
Common questions about Methyl Methyl Folate