Natural Factors
Berberine HCl 1000 mg
71/100
SUPPIE SCORE
80/100
EFFICACY
Medium
SAFETY
76/100
CLEANLINESS
What Does Berberine HCl 1000 mg Do?
Natural Factors Berberine HCl 1000 mg offers strong evidence-based support for blood sugar and metabolic health with optimal dosing. Generally safe for adults, but medium risk due to GI side effects and drug interactions; consult a doctor for personalized use.
What are the main benefits of berberine for blood sugar control?
How does berberine support cardiovascular health?
What dosage of berberine is recommended for metabolic health?
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What Are the Benefits of Berberine HCl 1000 mg?
Based on proven scientific research
Blood Sugar RegulationStrong
Cholesterol ManagementModerate
Weight ManagementModerate
Metabolic HealthStrong
Good For:
What Are the Side Effects of Natural Factors Berberine HCl 1000 mg?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•Berberine at 1000 mg daily may cause gastrointestinal side effects like diarrhea or constipation in sensitive individuals, as noted in clinical studies.
•Potential interactions with blood sugar-lowering medications (e.g., metformin) or CYP3A4-metabolized drugs (e.g., statins), requiring medical supervision to avoid hypoglycemia or altered drug levels.
•Dosage of 1000 mg (500 mg per capsule) aligns with safe, researched ranges up to 1500 mg daily for short-term use, per NIH and PubMed sources.
•Not recommended during pregnancy or breastfeeding due to potential uterine stimulant effects and lack of safety data; consult a doctor for elderly or children.
•Low allergen risk as gluten-free and vegan, but those with rice sensitivities should check; no major contamination concerns from reputable manufacturer Natural Factors.
•Long-term use beyond 3-6 months may affect gut microbiome or liver enzymes; monitor with healthcare provider.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
What Are the Ingredients in Natural Factors Berberine HCl 1000 mg?
Berberine HCl (from Berberis vulgaris extract) (root)
1000 mg
Vegetarian capsule (hypromellose, purified water)
Rice flour
Magnesium stearate (vegetable grade)
Silica
Stearic acid
Sources & References
Frequently Asked Questions
Common questions about Natural Factors Berberine HCl 1000 mg