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Natural Factors - BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12

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Natural Factors

BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12

B grade
86/100
SUPPIE SCORE
88/100
EFFICACY
High
SAFETY
82/100
CLEANLINESS

What Does BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12 Do?

- 1000 mcg 5-MTHF is a high, clearly disclosed folate dose. - Quatrefolic® 5-MTHF and methylcobalamin are bioactive forms with favorable usability. - Sublingual delivery may aid convenience, though B12 absorption remains dose-limited.
Is this methylfolate and B12 supplement suitable for someone with an MTHFR variant?
Can I take this product while trying to conceive or during early pregnancy?
Should this sublingual tablet be taken with food or on an empty stomach?
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What Are the Benefits of BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12?

Based on proven scientific research

Folate StatusVery strong
Vitamin B12 Deficiency PreventionStrong
Pregnancy Neural Tube SupportVery strong
Red Blood Cell FormationStrong
Energy MetabolismModerate

Good For:

What Are the Side Effects of Natural Factors BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12?

Always consult your health practitioner if in doubt.

RiskLow Risk

Overview

Provides a high folate dose at 1000 mcg 5-MTHF per tablet; this is a common upper supplemental range and should be used with clinician guidance if also taking prenatal vitamins or other high-folate products.
Vitamin B12 is supplied as methylcobalamin at 50 mcg, a high but generally well-tolerated water-soluble dose.
Folate can partially correct anemia signs while untreated vitamin B12 deficiency-related nerve issues persist; people with suspected B12 deficiency should seek medical assessment despite the included B12.
Appropriate for preconception and early pregnancy folate support per label directions, but pregnant or breastfeeding users should confirm total folate intake with a health professional.
OCR label states no dairy, wheat, gluten, soy, corn, egg, fish, shellfish, tree nuts, artificial colours, preservatives, or sweeteners, and indicates suitability for vegetarians/vegans.
Sublingual quick-dissolve tablets contain isomalt, which may cause mild digestive discomfort in sensitive individuals.

Potential Side Effects

Negative Interactions

Inactive Ingredients

Isomalt
Good
Cellulose
Low Risk
Croscarmellose sodium
Low Risk
Vegetable grade magnesium stearate
Low Risk

What Are the Ingredients in Natural Factors BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12?

Folate (from (6S)-5-methyltetrahydrofolic acid (MTHF), glucosamine salt, Quatrefolic®)
1000 mcg
Vitamin B12 (methylcobalamin)
50 mcg
Isomalt
cellulose
croscarmellose sodium
vegetable grade magnesium stearate

Frequently Asked Questions

Common questions about Natural Factors BioCoenzymated Methylfolate 1000 mcg plus cobalamin B12 50 mcg Folate + B12