Nature Made
D3 2000 IU (50 mcg)
88/100
SUPPIE SCORE
90/100
EFFICACY
High
SAFETY
84/100
CLEANLINESS
What Does D3 2000 IU (50 mcg) Do?
Nature Made D3 delivers an established 2000 IU maintenance dose of cholecalciferol supported by robust clinical research, complemented by a modest amount of calcium carbonate.
Should I take this Vitamin D3 tablet with a meal containing fats to maximize absorption?
How does 2000 IU of Vitamin D3 compare to the standard daily recommended allowance?
Are there any medication interactions I should be aware of before starting daily Vitamin D3?
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What Are the Benefits of D3 2000 IU (50 mcg)?
Based on proven scientific research
Bone DensityVery strong
Immune FunctionStrong
Muscle FunctionStrong
Good For:
What Are the Side Effects of Nature Made D3 2000 IU (50 mcg)?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•The 50 mcg (2000 IU) dose of Vitamin D3 is well below the established adult tolerable upper intake level (UL) of 100 mcg (4000 IU) per day.
•Supplements providing vitamin D3 and calcium carbonate may interact with thiazide diuretics, cardiac glycosides (digoxin), or certain tetracycline/quinolone antibiotics.
•Generally very well tolerated at this dose, though excessive long-term vitamin D intake can lead to hypercalcemia, nausea, or renal complications.
•Calcium carbonate may cause mild gastrointestinal side effects such as constipation or mild bloating in sensitive individuals.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Cellulose gel
Low RiskMaltodextrin
Low RiskSugar
Low RiskCroscarmellose sodium
Low RiskAcacia gum
GoodStearic acid
Low RiskCorn starch
Low RiskMagnesium stearate
Low RiskCellulose
Low RiskWhat Are the Ingredients in Nature Made D3 2000 IU (50 mcg)?
Vitamin D3 (as Cholecalciferol)
50 mcg (2000 IU)
Calcium (as Calcium Carbonate)
90 mg
Cellulose Gel
Maltodextrin
Sugar
Croscarmellose Sodium
Acacia Gum
Stearic Acid
Corn Starch
Magnesium Stearate
Cellulose
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Dosage & Bioavailability
How the active doses and forms in D3 2000 IU (50 mcg) compare to the research.
•Vitamin D3 (as Cholecalciferol) — 50 mcg (2000 IU); exceeds the adult RDA of 15 to 20 mcg (600 to 800 IU) and sits well within typical daily clinical repletion ranges of 1000.
•Vitamin D3 (as Cholecalciferol) — 50 mcg (2000 IU); provided as cholecalciferol, which exhibits superior bioavailability and sustained serum 25(OH)D elevation compared.
•Calcium (as Calcium Carbonate) — 90 mg; represents a small fractional contribution relative to the standard adult RDA of 1000 to 1200 mg, requiring stomach acid for optimal.
Sources & References
Frequently Asked Questions
Common questions about Nature Made D3 2000 IU (50 mcg)