NOW
Vitamin D3 & K2 1,000 IU / 45 mcg
87/100
SUPPIE SCORE
78/100
EFFICACY
High
SAFETY
92/100
CLEANLINESS
What Does Vitamin D3 & K2 1,000 IU / 45 mcg Do?
Provides standard maintenance doses of vitamin D3 and K2 to support bone mineralisation and calcium handling, though the K2 dose is modest.
Is 1,000 IU of vitamin D3 enough to correct a deficiency?
Can I take this supplement if I take warfarin?
Why does this formula use vitamin K2 alongside D3?
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What Are the Benefits of Vitamin D3 & K2 1,000 IU / 45 mcg?
Based on proven scientific research
Maintains 25-hydroxyvitamin D levelsVery strong
Supports intestinal calcium absorptionVery strong
Carboxylation of bone and vascular proteinsModerate
Good For:
What Are the Side Effects of NOW Vitamin D3 & K2 1,000 IU / 45 mcg?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Vitamin D 1000 IU daily is below the 4000 IU UL and commonly used to support status in low-sunlight regions or older adults.
•K2 45 mcg is a low supplemental dose; evidence for cardiovascular or bone effects at this level is limited compared with 180 mcg trials.
•No major drug interactions expected at these doses; vitamin D can theoretically raise calcium levels if combined with high-dose calcium and thiazides.
•Safe in pregnancy at this dose per routine guidance; no specific allergen concerns from the actives.
•Stop and get advice if: numbness, tingling, or persistent nausea: possible hypercalcemia from vitamin D; seek medical advice.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Rice flour
Low RiskHypromellose (cellulose apoda)
Low RiskAscorbyl palmitate
GoodSilicon dioxide
Low RiskWhat Are the Ingredients in NOW Vitamin D3 & K2 1,000 IU / 45 mcg?
Vitamin D (1,000 lU)
25 mcg
Vitamin K2
45 mcg
Rice Flour
Hypromellose (cellulose apoda)
Ascorbyl Palmitate
Silicon Dioxide
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Dosage & Bioavailability
How the active doses and forms in Vitamin D3 & K2 1,000 IU / 45 mcg compare to the research.
•Vitamin D (1,000 lU) — 25-50 mcg a day; within the 25-100 mcg/day for supplementation in adults used in studies.
•Vitamin K2 — 45-90 mcg a day; studies use 90-1,000 mcg/day. The higher daily dose reaches it; the lowest falls short.
Sources & References
Should vitamin k be supplemented alongside vitamin d
Information from examine.com
PMC8067486
Information from pmc.ncbi.nlm.nih.gov
220788
Information from dsld.od.nih.gov
39125301
Information from pubmed.ncbi.nlm.nih.gov
PMC9237441
Information from pmc.ncbi.nlm.nih.gov
VitaminD HealthProfessional
Information from ods.od.nih.gov
Frequently Asked Questions
Common questions about NOW Vitamin D3 & K2 1,000 IU / 45 mcg