Orthoplex
Indol-Active DIM Powder 60g
71/100
SUPPIE SCORE
62/100
EFFICACY
Medium
SAFETY
90/100
CLEANLINESS
What Does Indol-Active DIM Powder 60g Do?
Orthoplex Indol-Active DIM delivers liposomal diindolylmethane formulated for compounding to influence estrogen metabolism pathways, though human clinical evidence remains primarily focused on urinary metabolite biomarker shifts.
What is the clinical evidence supporting liposomal DIM for estrogen balance?
Can taking Indol-Active DIM interfere with birth control or hormone therapy?
How should this extemporaneous compounding powder be dosed and administered?
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What Are the Benefits of Indol-Active DIM Powder 60g?
Based on proven scientific research
Estrogen Metabolism ModulationModerate
Glucuronidation & Detoxification SupportMild
Hormonal Balance SupportMild
Good For:
What Are the Side Effects of Orthoplex Indol-Active DIM Powder 60g?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•Interactions with hormonal therapies: DIM alters estrogen hydroxylation pathways and may reduce the efficacy or predictability of oral contraceptives, hormone replacement therapy, and anti-estrogen medications such as tamoxifen.
•Cytochrome P450 interactions: DIM is a known inducer of CYP1A2 and may alter the clearance rates of medications metabolised through hepatic phase I and glucuronidation pathways.
•Pregnancy and lactation: DIM influences sex hormone receptor binding and metabolism; strictly avoid use during pregnancy and breastfeeding unless explicitly directed by a physician.
•Gastrointestinal and headache reactions: common adverse effects reported in DIM supplementation include transient headaches, nausea, mild gastrointestinal upset, and harmless dark urine discolouration.
•Compounding base usage: formulated specifically for extemporaneous compounding under practitioner direction, meaning standard dosage and duration must be supervised.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Calcium d-glucarate (calcium saccharate)
Low RiskGlycine
Low RiskColloidal anhydrous silica
Low RiskSunflower lecithin
Low RiskAcacia
GoodWhat Are the Ingredients in Orthoplex Indol-Active DIM Powder 60g?
Indol-Active liposomal DIM (providing 3,3'-Diindolylmethane 45 mg)
183.7mg
Calcium D-glucarate (calcium saccharate)
Glycine
Colloidal anhydrous silica
Sunflower lecithin
Acacia
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Dosage & Bioavailability
How the active doses and forms in Indol-Active DIM Powder 60g compare to the research.
•Indol-Active liposomal DIM (providing 3,3'-Diindolylmethane 45 mg) — no studied range to compare this dose with yet.
Frequently Asked Questions
Common questions about Orthoplex Indol-Active DIM Powder 60g