SISU
SISU B Calm with Rhodiola
75/100
SUPPIE SCORE
72/100
EFFICACY
Medium
SAFETY
92/100
CLEANLINESS
What Does SISU B Calm with Rhodiola Do?
Its main active, Medicinal ingredients Vitamin B1 (thiamine) (thiamine hydrochloride), provides 25 mg a day, within the range studies typically use (5-500 mg/day). Vitamin B6 (pyridoxine hydrochloride & pyridoxal-5-phosphate) is over its 12 mg/day upper limit.
How long should I take this before expecting benefits?
Can I combine this with other B-vitamin or adaptogen products?
What monitoring is recommended with the 50 mg B6 dose?
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What Are the Benefits of SISU B Calm with Rhodiola?
Based on proven scientific research
StressModerate
FatigueModerate
Energy metabolismStrong
Cognitive supportMild
Good For:
What Are the Side Effects of SISU SISU B Calm with Rhodiola?
Always consult your health practitioner if in doubt.
RiskMedium Risk
Overview
•Vitamin B6: 50 mg a day is above the 12 mg/day EU upper limit (EFSA 2023), though within the US limit of 100 mg/day. Taking more than this for months is linked to nerve damage (peripheral neuropathy: numbness, tingling or pain in hands and feet), which usually improves after stopping.
•Rhodiola rosea at 250 mg standardized extract (1% salidroside) may cause dizziness, headache or insomnia in some users.
•High-dose B6 (50 mg daily) can reduce anxiety but monitor for sensory neuropathy with prolonged use above 50 mg.
•Rhodiola may interact with losartan and other blood-pressure medications via reported case evidence.
•Folate (200 mcg) and methylcobalamin forms support use but evidence limited for long-term high-B complex safety in all populations.
Potential Side Effects
Negative Interactions
Allergens
Vegetable magnesium stearate source
Inactive Ingredients
Microcrystalline cellulose
Low RiskMagnesium stearate (vegetable)
Low RiskMaybe this product has something to do with it. i do find it has a tiny after taste
Low RiskWhat Are the Ingredients in SISU SISU B Calm with Rhodiola?
Medicinal ingredients Vitamin B1 (thiamine) (thiamine hydrochloride)
25 mg
Vitamin B2 (riboflavin) (riboflavin & riboflavin-5-phosphate [sodium salt])
25 mg
Vitamin B6 (pyridoxine hydrochloride & pyridoxal-5-phosphate)
50 mg
Vitamin B3 (niacinamide)
20 mg
Vitamin B5 (pantothenic acid) (calcium-d-pantothenate)
100 mg
Vitamin B9 (folate) (folic acid)
200 mcg
Biotin
75 mcg
Vitamin B12 (methylcobalamin)
100 mcg
Roseroot (Rhodiola rosea) root extract standardized to contain 1% salidrosides
250 mg
Microcrystalline cellulose
magnesium stearate (vegetable)
maybe this product has something to do with it. I do find it has a tiny after taste
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Dosage & Bioavailability
How the active doses and forms in SISU B Calm with Rhodiola compare to the research.
•Medicinal ingredients Vitamin B1 (thiamine) (thiamine hydrochloride) — 25 mg per capsule, 1 capsule a day: 25 mg a day; within the 5-500 mg/day typically used in studies. This range is provisional until reviewed.
•Vitamin B6 (pyridoxine hydrochloride & pyridoxal-5-phosphate) — 50 mg per capsule, 1 capsule a day: 50 mg a day is over the 12 mg/day upper limit (EFSA 2023); the US limit is 100 mg/day (IOM (NIH ODS)).
•3 of 8 actives with a studied range are below it.
Sources & References
Sisu b calm with rhodiola 56720.html
Information from well.ca
38972090
Information from pubmed.ncbi.nlm.nih.gov
PMC11610317
Information from pmc.ncbi.nlm.nih.gov
PMC10343656
Information from pmc.ncbi.nlm.nih.gov
34432056
Information from pubmed.ncbi.nlm.nih.gov
Rhodiola
Information from www.nccih.nih.gov
Frequently Asked Questions
Common questions about SISU SISU B Calm with Rhodiola