Solgar
No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50
79/100
SUPPIE SCORE
52/100
EFFICACY
High
SAFETY
90/100
CLEANLINESS
What Does No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50 Do?
Provides inositol hexanicotinate to avoid flushing, but human trials demonstrate minimal hydrolysis into free nicotinic acid and negligible lipid-modifying efficacy.
Does no-flush niacin lower cholesterol the same way as standard niacin?
Why does this form of niacin not cause tingling or facial redness?
Can inositol hexanicotinate cause liver toxicity at high daily doses?
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What Are the Benefits of No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50?
Based on proven scientific research
Niacin deficiency preventionModerate
Flush-free tolerabilityStrong
Peripheral circulation supportMild
Good For:
What Are the Side Effects of Solgar No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50?
Always consult your health practitioner if in doubt.
RiskLow Risk
Overview
•Inositol hexanicotinate: No upper limit is set for inositol hexanicotinate itself: it releases little free nicotinic acid, so the 35 mg/day US niacin limit, set on nicotinic-acid flushing, does not fit it. EFSA applies its 10 mg/day nicotinic-acid limit to it as a precaution.
•Inositol hexanicotinate eliminates the benign but uncomfortable prostaglandin-mediated flush characteristic of free nicotinic acid.
•Although generally well tolerated at 500–1,000 mg daily, very high intake of niacin derivatives warrants monitoring of liver function enzymes in predisposed individuals.
•May exert mild additive vasodilatory or hypotensive effects when combined with antihypertensive prescription medications.
•People with active liver disease, peptic ulcer disease, or severe gout should use high-dose vitamin B3 compounds only under medical supervision.
•Safety data during pregnancy and lactation are limited for megadose inositol hexanicotinate; stick to standard prenatal multivitamin amounts.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Hydroxypropylmethyl cellulose
Low RiskSilicon dioxide
Low RiskVegetable magnesium stearate
Low RiskWhat Are the Ingredients in Solgar No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50?
Inositol hexanicotinate
500mg
hydroxypropylmethyl cellulose
silicon dioxide
vegetable magnesium stearate
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Dosage & Bioavailability
How the active doses and forms in No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50 compare to the research.
•Inositol hexanicotinate — 500 mg per capsule, 1-2 capsules a day: 500-1,000 mg a day; studies typically use 14-35 mg/day. No upper limit is set for inositol hexanicotinate itself: it releases little free nicotinic acid, so the 35 mg/day US niacin limit, set on nicotinic-acid flushing, does not fit it. EFSA applies its 10 mg/day nicotinic-acid limit to it as a precaution. This range is provisional until reviewed.
•Inositol hexanicotinate — inositol hexanicotinate is a less well absorbed form of vitamin B3 than Nicotinamide (niacinamide): no flushing or Nicotinic acid (niacin): flushing at low doses.
Frequently Asked Questions
Common questions about Solgar No-Flush Niacin 500 mg Vegetable Capsules — Pack of 50