WAGNER
CLOMIPRAMINE-WGR
46/100
SUPPIE SCORE
85/100
EFFICACY
Low
SAFETY
42/100
CLEANLINESS
What Does CLOMIPRAMINE-WGR Do?
Clomipramine-WGR 25mg is highly effective for OCD and depression with strong RCT and meta-analysis support, starting at a safe low dose but requiring titration. Safety concerns are significant due to cardiac, seizure, and interaction risks, necessitating close medical monitoring.
What are the primary indications for clomipramine in treating OCD and depression?
How does clomipramine compare to SSRIs in terms of efficacy and side effects?
What monitoring is required during clomipramine treatment?
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What Are the Benefits of CLOMIPRAMINE-WGR?
Based on proven scientific research
Obsessive-Compulsive DisorderVery strong
DepressionStrong
PhobiasModerate
Cataplexy in NarcolepsyModerate
Good For:
What Are the Side Effects of WAGNER CLOMIPRAMINE-WGR?
Always consult your health practitioner if in doubt.
RiskHigh Risk
Overview
•Clomipramine hydrochloride at 25mg is a low starting dose within safe limits for adults, but requires gradual titration to effective ranges (50-250mg/day) under medical supervision to minimize anticholinergic and cardiovascular side effects.
•Common side effects include dry mouth, constipation, drowsiness, and sexual dysfunction due to tricyclic antidepressant properties; serious risks involve cardiac arrhythmias, seizures, and serotonin syndrome with interactions.
•High interaction potential with MAOIs, SSRIs, antihypertensives, and grapefruit juice; contraindicated with recent heart attack, glaucoma, or prostate issues in this formulation.
•Not suitable for pregnancy (Category C) or breastfeeding due to risks to fetus/newborn like withdrawal symptoms; higher risks in elderly for confusion and falls.
•Contains lactose, posing risks for lactose-intolerant individuals; no gluten or tartrazine, but monitor for allergic reactions to any excipients.
•Long-term use may increase bone fracture risk and requires ECG monitoring for QT prolongation, especially at higher doses beyond the 25mg per tablet.
Potential Side Effects
Negative Interactions
Inactive Ingredients
Medium Risk
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
Low Risk
What Are the Ingredients in WAGNER CLOMIPRAMINE-WGR?
clomipramine hydrochloride
25 mg
Lactose monohydrate
Microcrystalline cellulose
Croscarmellose sodium
Magnesium stearate
Colloidal anhydrous silica
Hypromellose
Macrogol 3350
Titanium dioxide
Iron oxide yellow
Sources & References
Clomipramine anafranil
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Information from www.cvs.com
Appi.ps.54.8.1111
Information from psychiatryonline.org
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Information from www.cambridge.org
Clomipramine wgr tablets
Information from www.nps.org.au
Drg 20072005
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Augmenting selective serotonin reuptake inhibitors
Information from www.psychiatrist.com
S0033318283731671
Information from www.sciencedirect.com
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Information from pubmed.ncbi.nlm.nih.gov
Clomipramine wgr
Information from www.healthdirect.gov.au
19957 clomipramine capsules
Information from my.clevelandclinic.org
1770141000168101.html
Information from m.pbs.gov.au
Full
Information from www.frontiersin.org
Clomipramine
Information from www.sciencedirect.com
Frequently Asked Questions
Common questions about WAGNER CLOMIPRAMINE-WGR